Diabetes and Protein Glycosylation

Measurement and Biologic Relevance

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Endocrinology & Metabolism, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book Diabetes and Protein Glycosylation by Margo Panush Cohen, Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Margo Panush Cohen ISBN: 9781461249382
Publisher: Springer New York Publication: December 6, 2012
Imprint: Springer Language: English
Author: Margo Panush Cohen
ISBN: 9781461249382
Publisher: Springer New York
Publication: December 6, 2012
Imprint: Springer
Language: English

In the years since the initial discovery that blood from diabetic patients contains increased amounts of a posttranslationally gluco­ sylated form of hemoglobin (hemoglobin Ale)' an impressive number of studies have clarified and expanded the use of glycohemoglobin levels to assess disease status. Many other structural proteins have been shown to undergo similar changes, including proteins from tissues most commonly affected in diabetes (e.g., lens, aorta, peripheral nerve, basement membrane). Thus, the nonenzymatic glycosylation of hemoglobin emerges as an invaluable model for the pathogenesis of certain chronic diabetes complications. In addition to reviewing a wealth of investigative possibilities in the area of these chronic complications-including eye, kidney, nerve, and vascular disease-Dr. Cohen indicates how enhanced nonenzymatic glycosylation in uncontrolled diabetes underscores the pressing need for maintenance of long-term euglycemia. Dr. Cohen is an endocrinologist and diabetes specialist whose research activities have largely focused on the chemistry and metabo­ lism of the basement membrane in diabetes. This superb monograph on nonenzymatic glycosylation clearly shows the major trends of her past and present research and clinical activities. This book is beautifully written and a pleasure to read. It provides great insight into the mechanisms of the pathogenesis of the oom- vii viii Foreword cations of diabetes and should be of immense value not only to basic and clinical investigators, but also to internists, diabetologists, and endocrinologists in clinical practice.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In the years since the initial discovery that blood from diabetic patients contains increased amounts of a posttranslationally gluco­ sylated form of hemoglobin (hemoglobin Ale)' an impressive number of studies have clarified and expanded the use of glycohemoglobin levels to assess disease status. Many other structural proteins have been shown to undergo similar changes, including proteins from tissues most commonly affected in diabetes (e.g., lens, aorta, peripheral nerve, basement membrane). Thus, the nonenzymatic glycosylation of hemoglobin emerges as an invaluable model for the pathogenesis of certain chronic diabetes complications. In addition to reviewing a wealth of investigative possibilities in the area of these chronic complications-including eye, kidney, nerve, and vascular disease-Dr. Cohen indicates how enhanced nonenzymatic glycosylation in uncontrolled diabetes underscores the pressing need for maintenance of long-term euglycemia. Dr. Cohen is an endocrinologist and diabetes specialist whose research activities have largely focused on the chemistry and metabo­ lism of the basement membrane in diabetes. This superb monograph on nonenzymatic glycosylation clearly shows the major trends of her past and present research and clinical activities. This book is beautifully written and a pleasure to read. It provides great insight into the mechanisms of the pathogenesis of the oom- vii viii Foreword cations of diabetes and should be of immense value not only to basic and clinical investigators, but also to internists, diabetologists, and endocrinologists in clinical practice.

More books from Springer New York

Cover of the book Cross-Sectional Imaging of the Abdomen and Pelvis by Margo Panush Cohen
Cover of the book Current Topics in Innate Immunity II by Margo Panush Cohen
Cover of the book Surgical Techniques for Kidney Cancer by Margo Panush Cohen
Cover of the book Pediatric Urology by Margo Panush Cohen
Cover of the book Handbook on the Neuropsychology of Aging and Dementia by Margo Panush Cohen
Cover of the book Regression Methods in Biostatistics by Margo Panush Cohen
Cover of the book Antioxidant Properties of Spices, Herbs and Other Sources by Margo Panush Cohen
Cover of the book Statistics and Data Analysis for Financial Engineering by Margo Panush Cohen
Cover of the book Inherited Cancer Syndromes by Margo Panush Cohen
Cover of the book Geothermal Engineering by Margo Panush Cohen
Cover of the book Modes of Action of GnRH and GnRH Analogs by Margo Panush Cohen
Cover of the book Oral Delivery of Macromolecular Drugs by Margo Panush Cohen
Cover of the book Residue Reviews by Margo Panush Cohen
Cover of the book Biosonar by Margo Panush Cohen
Cover of the book Simplicial Structures in Topology by Margo Panush Cohen
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy