Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Specialties, Oncology
Cover of the book Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319211008
Publisher: Springer International Publishing Publication: August 1, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783319211008
Publisher: Springer International Publishing
Publication: August 1, 2015
Imprint: Springer
Language: English

Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries.  In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection.  Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity.

This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume.  This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries.  In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection.  Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity.

This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume.  This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.

More books from Springer International Publishing

Cover of the book Surface Analysis and Techniques in Biology by
Cover of the book Theory and Models for Cyber Situation Awareness by
Cover of the book Relativistic Geodesy by
Cover of the book University Initiatives in Climate Change Mitigation and Adaptation by
Cover of the book Globular Cluster Binaries and Gravitational Wave Parameter Estimation by
Cover of the book Termites and Sustainable Management by
Cover of the book The U.S. Foreign Language Deficit by
Cover of the book Conceiving Mozambique by
Cover of the book Structural Health Monitoring, Volume 5 by
Cover of the book Data Privacy Management, Cryptocurrencies and Blockchain Technology by
Cover of the book Teaching Victorian Literature in the Twenty-First Century by
Cover of the book Focus on Gynecologic Malignancies by
Cover of the book James Bond Uncovered by
Cover of the book Post-Quantum Cryptography by
Cover of the book SMART Supply Network by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy