Pharmacology of Itch

Nonfiction, Health & Well Being, Medical, Specialties, Anesthesiology, Medical Science, Pharmacology
Cover of the book Pharmacology of Itch by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783662446058
Publisher: Springer Berlin Heidelberg Publication: April 10, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783662446058
Publisher: Springer Berlin Heidelberg
Publication: April 10, 2015
Imprint: Springer
Language: English

Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its complexity and its negative effects on the quality of life of the distressed patients. Like pain, not all itches are the same. Unlike pain, there are no standard drugs equivalent to aspirin and morphine. Epidemiological studies emphasize the high incidence and economic costs of itch (pruritus). It is the most prevalent symptom of a wide variety of allergic and inflammatory skin conditions (e.g., psoriasis, atopic dermatitis), is associated with several systemic diseases (e.g., chronic kidney and liver disease), and occurs in patients undergoing hemodialysis, spinal administration of opioids, and in those suffering from AIDS. The reader will learn about the multiple pathways for itch and their interactions with pain. The relationship between these closely related, yet distinct sensory phenomena, will be emphasized. Both itch and pain use several common molecules to send signals to the brain. Thus, drugs that have been, and are being, developed as analgesics may also attenuate intractable itch. This has been an exciting and very necessary turn of events since traditional H-1 receptor antagonists are ineffective in blocking the pruritus associated with kidney failure and cholestasis. The clinical chapters will provide insights into contemporary treatment regimens for pruritus in different human scenarios.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its complexity and its negative effects on the quality of life of the distressed patients. Like pain, not all itches are the same. Unlike pain, there are no standard drugs equivalent to aspirin and morphine. Epidemiological studies emphasize the high incidence and economic costs of itch (pruritus). It is the most prevalent symptom of a wide variety of allergic and inflammatory skin conditions (e.g., psoriasis, atopic dermatitis), is associated with several systemic diseases (e.g., chronic kidney and liver disease), and occurs in patients undergoing hemodialysis, spinal administration of opioids, and in those suffering from AIDS. The reader will learn about the multiple pathways for itch and their interactions with pain. The relationship between these closely related, yet distinct sensory phenomena, will be emphasized. Both itch and pain use several common molecules to send signals to the brain. Thus, drugs that have been, and are being, developed as analgesics may also attenuate intractable itch. This has been an exciting and very necessary turn of events since traditional H-1 receptor antagonists are ineffective in blocking the pruritus associated with kidney failure and cholestasis. The clinical chapters will provide insights into contemporary treatment regimens for pruritus in different human scenarios.

More books from Springer Berlin Heidelberg

Cover of the book Ölhydraulik by
Cover of the book Usability-Engineering in der Medizintechnik by
Cover of the book Flexible Intramedullary Nailing in Children by
Cover of the book Basic and Clinical Research on Renal Cell Carcinoma by
Cover of the book Fiber-Shaped Energy Harvesting and Storage Devices by
Cover of the book Quality and Treatment of Drinking Water II by
Cover of the book Technologie von Unternehmenssoftware by
Cover of the book Endlich gelöst! Aufgaben zur Mathematik für Ingenieure und Naturwissenschaftler by
Cover of the book Evolutionary Biology - Concepts, Molecular and Morphological Evolution by
Cover of the book Surgical Anatomy of the Internal Carotid Artery by
Cover of the book International Neurolaw by
Cover of the book Political Ethics and European Constitution by
Cover of the book Diagnosis and Treatment of Senile Dementia by
Cover of the book The Causes of Economic Growth by
Cover of the book Funktionelle Schmerztherapie des Bewegungssystems by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy