Structural Genomics, Part B

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Genetics
Cover of the book Structural Genomics, Part B by , Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9780080922386
Publisher: Elsevier Science Publication: November 26, 2009
Imprint: Academic Press Language: English
Author:
ISBN: 9780080922386
Publisher: Elsevier Science
Publication: November 26, 2009
Imprint: Academic Press
Language: English

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.

While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

  • Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy
  • Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.

While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

More books from Elsevier Science

Cover of the book Sediments, Diagenesis, and Sedimentary Rocks by
Cover of the book Marine Medicinal Foods by
Cover of the book Telemental Health by
Cover of the book Organizational Learning in Asia by
Cover of the book Shoulder and Elbow Trauma and its Complications by
Cover of the book Biofluid Mechanics by
Cover of the book Research Advances in Rabies by
Cover of the book Polymer-based Nanocomposites for Energy and Environmental Applications by
Cover of the book Positive Youth Development by
Cover of the book Spatial Capture-Recapture by
Cover of the book Atomic Force Microscopy in Process Engineering by
Cover of the book Advances in Marine Biology by
Cover of the book Bank Risk Management in Developing Economies by
Cover of the book Information Protection Playbook by
Cover of the book Physics and Engineering of Radiation Detection by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy