Topology and Physics of Circular DNA (1992)

Nonfiction, Health & Well Being, Medical, Medical Science, Biochemistry, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Genetics
Cover of the book Topology and Physics of Circular DNA (1992) by Alexander Vologodskii, CRC Press
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Author: Alexander Vologodskii ISBN: 9781351355827
Publisher: CRC Press Publication: November 22, 2017
Imprint: CRC Press Language: English
Author: Alexander Vologodskii
ISBN: 9781351355827
Publisher: CRC Press
Publication: November 22, 2017
Imprint: CRC Press
Language: English

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

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Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

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