Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism by Lorenzo Galluzzi, Guido Kroemer, Elsevier Science
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Author: Lorenzo Galluzzi, Guido Kroemer ISBN: 9780124166578
Publisher: Elsevier Science Publication: May 23, 2014
Imprint: Academic Press Language: English
Author: Lorenzo Galluzzi, Guido Kroemer
ISBN: 9780124166578
Publisher: Elsevier Science
Publication: May 23, 2014
Imprint: Academic Press
Language: English

Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

  • Continues the legacy of this premier serial with quality chapters authored by leaders in the field
  • Covers research methods in biomineralization science
  • Provides theoretical overview on metabolic alterations of cancer cells, and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

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