Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Physiology
Cover of the book Leucocyte Trafficking by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg Publication: June 29, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg
Publication: June 29, 2013
Imprint: Springer
Language: English

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

More books from Springer Berlin Heidelberg

Cover of the book Random Walks and Diffusions on Graphs and Databases by
Cover of the book Neurodegenerative Diseases by
Cover of the book Introduction to Probability and Statistics for Engineers by
Cover of the book Fundamentals of Geophysical Hydrodynamics by
Cover of the book Procedural Rights in Competition Law in the EU and China by
Cover of the book Terrestrial Heat Flow and the Lithosphere Structure by
Cover of the book Kraftvoll ins Wasser by
Cover of the book Nursing Law and Ethics by
Cover of the book Thermal Separation Technology by
Cover of the book Pharmaceuticals in the Environment by
Cover of the book Quality-aware Scheduling for Key-value Data Stores by
Cover of the book Green Building by
Cover of the book Production Systems and Supply Chain Management in Emerging Countries: Best Practices by
Cover of the book Footprints in Micrometeorology and Ecology by
Cover of the book Basic and Clinical Research on Renal Cell Carcinoma by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy