Synthesis of new isatin derivatives for possible CNS activity

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Synthesis of new isatin derivatives for possible CNS activity by Kiran Gangarapu, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Kiran Gangarapu ISBN: 9783656622727
Publisher: GRIN Verlag Publication: March 25, 2014
Imprint: GRIN Verlag Language: English
Author: Kiran Gangarapu
ISBN: 9783656622727
Publisher: GRIN Verlag
Publication: March 25, 2014
Imprint: GRIN Verlag
Language: English

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

More books from GRIN Verlag

Cover of the book Die Emanzipation der Frau in Armonía Somers' 'El derrumbamiento' by Kiran Gangarapu
Cover of the book Erfahrungswerte der Abrechnung von gebührenrechtlichen Honorarpositionen bei mund-, kiefer- und gesichtschirurgischen Vertragsleistungen by Kiran Gangarapu
Cover of the book Trainingslehre 1. Praxisanalyse mit einer 20-jährigen Kandidatin by Kiran Gangarapu
Cover of the book Sprachliche Förderung von Kindern mit Autismus by Kiran Gangarapu
Cover of the book Digitalisierung und Qualitätsmanagement in der Jugendhilfe by Kiran Gangarapu
Cover of the book Der Fusionsreaktor - Ablauf der Kernfusion und Reaktorkonzepte by Kiran Gangarapu
Cover of the book Die Problematik jüdischer Apotheker, Pharmazie- und Medizinstudenten im Vormärz am Beispiel des 'Apotheker-Subjects' Leo Piepes und seines Umfeldes by Kiran Gangarapu
Cover of the book Organisationsdiagnostik by Kiran Gangarapu
Cover of the book Grundlagen der Telearbeit - Voraussetzungen und Möglichkeiten - ein kurzer Überblick by Kiran Gangarapu
Cover of the book Cicero, de re publica 1, 54-71 by Kiran Gangarapu
Cover of the book Die Sprache des Plakats. Die Text-Bild-Beziehung anhand zweier Werbeplakate by Kiran Gangarapu
Cover of the book BIM Kongress 2014. Tagungsband by Kiran Gangarapu
Cover of the book Artikel 20a GG: Umweltschutz als Staatsziel by Kiran Gangarapu
Cover of the book Hochbegabung im Grundschulalter by Kiran Gangarapu
Cover of the book Angebote erfolgreich formulieren by Kiran Gangarapu
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy